Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 6/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.48 |
| ▸ | GALR3 | O60755 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254946 | 0.87 | EGFR (0.59) | CYP1A2KDREGFRAURKBCLK4 | |
| SCHEMBL11248666 | 0.83 | CYP1A2 (0.54) | CYP1A2KDREGFRAURKBCLK4 | |
| SCHEMBL19728993 | 0.77 | CYP1A2 (0.69) | CYP1A2EGFRAURKBCLK4ERBB2 | |
| SCHEMBL11245793 | 0.74 | EGFR (0.54) | CYP1A2KDRTEKEGFRAURKB | |
| SCHEMBL11260593 | 0.72 | PIK3CD (0.71) | KDRTEKEGFRAURKBCLK4 | |
| SCHEMBL11256846 | 0.72 | NR2F2 (0.59) | CYP1A2KDRTEKEGFRAURKB | |
| SCHEMBL11246622 | 0.71 | PIK3CD (0.66) | KDRTEKEGFRAURKBCLK4 | |
| SCHEMBL11242092 | 0.70 | LMNA (0.66) | KDRTEKEGFRAURKBCLK4 | |
| Water SCHEMBL11248657 | 0.69 | LMNA (0.64) | KDRTEKEGFRAURKBCLK4 | |
| SCHEMBL11247664 | 0.69 | LMNA (0.68) | KDRTEKEGFRAURKBCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |