Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | LTK | P29376 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250839 | 0.83 | CYP1A2 (0.58) | CYP1A2SMN1; SMN2MAPK1GAAHTT | |
| SCHEMBL11254946 | 0.77 | EGFR (0.59) | CYP1A2SMN1; SMN2MAPK1HTTALOX15 | |
| SCHEMBL11249608 | 0.76 | LDHA (0.68) | CYP1A2SMN1; SMN2MAPK1GAAHTT | |
| SCHEMBL11246726 | 0.76 | LDHA (0.50) | CYP1A2PKMSMN1; SMN2MAPK1GAA | |
| SCHEMBL11255217 | 0.75 | LDHA (0.63) | CYP1A2SMN1; SMN2MAPK1GAAHTT | |
| SCHEMBL11254495 | 0.74 | SMN1; SMN2 (0.64) | CYP1A2SMN1; SMN2MAPK1GAAHTT | |
| SCHEMBL11245960 | 0.74 | NR2F2 (0.52) | CYP1A2PKMSMN1; SMN2MAPK1GAA | |
| SCHEMBL19728993 | 0.74 | CYP1A2 (0.69) | CYP1A2PKMSMN1; SMN2MAPK1GAA | |
| SCHEMBL11248365 | 0.73 | SMN1; SMN2 (0.66) | CYP1A2SMN1; SMN2MAPK1GAAHTT | |
| SCHEMBL11243467 | 0.73 | SMN1; SMN2 (0.66) | CYP1A2SMN1; SMN2MAPK1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | claimed |
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |