Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257093 | 0.83 | MAPK13 (0.42) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11253756 | 0.81 | MAPT (0.45) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13318454 | 0.76 | ALDH1A1 (0.66) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9326699 | 0.71 | MEN1 (0.66) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11260264 | 0.69 | ALDH1A1 (0.50) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9326744 | 0.68 | NPC1 (0.43) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| Diphenylamine SCHEMBL28553827 | 0.68 | MAPT (0.71) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| Diphenylamine SCHEMBL374606 | 0.68 | MAPT (0.71) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| Diphenylamine SCHEMBL6904395 | 0.68 | MAPT (0.71) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL24437356 | 0.67 | KMT2A (0.58) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | claimed |
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | disclosed |