Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260264 | 0.89 | ALDH1A1 (0.50) | MAPTLMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11269692 | 0.86 | KMT2A (0.51) | MAPTLMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11268463 | 0.81 | CASP3 (0.48) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11250906 | 0.81 | MAPT (0.42) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11257093 | 0.77 | MAPK13 (0.42) | MAPTLMNAMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL11263016 | 0.73 | ALDH1A1 (0.42) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11254698 | 0.72 | KDM4E (0.43) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11254861 | 0.71 | CHRM2 (0.44) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL13318454 | 0.71 | ALDH1A1 (0.66) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL11263457 | 0.70 | CASP3 (0.45) | LMNAKDM4ETHRBALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | claimed |
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | disclosed |