Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243111 | 0.89 | LMNA (0.41) | TP53GAALMNAHTTMAPT | |
| SCHEMBL11245143 | 0.87 | HPGD (0.44) | TP53GAASMN1; SMN2POLBAKR1C3 | |
| SCHEMBL11403084 | 0.77 | POLB (0.41) | TP53LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL11178376 | 0.73 | IMPDH2 (0.39) | GAALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2771325 | 0.73 | TP53 (0.56) | TP53GAALMNAHTTMAPT | |
| SCHEMBL9217336 | 0.72 | AKR1C3 (0.68) | TP53HTTMAPTPOLBAKR1C3 | |
| SCHEMBL28384878 | 0.71 | AKR1C3 (0.61) | TP53GAALMNAHTTMAPT | |
| SCHEMBL257274 | 0.71 | MAPT (0.62) | TP53GAALMNAHTTMAPT | |
| SCHEMBL2528738 | 0.71 | C5AR1 (0.70) | GAALMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL10801707 | 0.71 | NPSR1 (0.55) | TP53GAALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316042-A | Substituted carboxyalkoxyaminodihydrobenzophenones | SANDOZ LTD. (CH) | 1982-02-16 | — | — | US | disclosed |