Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253237 | 1.00 | KMT2A (0.43) | KMT2AMAPTMEN1TSHRPOLB | |
| SCHEMBL11264615 | 0.88 | NPC1 (0.40) | KMT2AMAPTTSHRHDAC3NPC1 | |
| SCHEMBL9329375 | 0.88 | NPC1 (0.40) | KMT2AMAPTTSHRHDAC3NPC1 | |
| SCHEMBL9143119 | 0.80 | CES2 (0.47) | KMT2AMEN1POLBNPC1CES2 | |
| SCHEMBL6878186 | 0.80 | CES2 (0.47) | KMT2AMEN1POLBNPC1CES2 | |
| SCHEMBL6878184 | 0.80 | CES2 (0.47) | KMT2AMEN1POLBNPC1CES2 | |
| SCHEMBL9864813 | 0.79 | PTPN1 (0.41) | KMT2AMAPTMEN1POLBNPC1 | |
| SCHEMBL10774849 | 0.79 | PTPN1 (0.41) | KMT2AMAPTMEN1POLBNPC1 | |
| SCHEMBL9864807 | 0.79 | PTPN1 (0.41) | KMT2AMAPTMEN1POLBNPC1 | |
| SCHEMBL11137416 | 0.78 | KMT2A (0.45) | KMT2AMAPTMEN1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350694-A | OXACEPHALOSPORINS/; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4234724-A | OXADETHIACEPHEMCARBOXYLIC ACIDS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-11-18 | — | — | US | disclosed |