Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774849 | 1.00 | PTPN1 (0.41) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL9864813 | 1.00 | PTPN1 (0.41) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL11264615 | 0.82 | NPC1 (0.40) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL9329375 | 0.82 | NPC1 (0.40) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL11253237 | 0.79 | KMT2A (0.43) | CES2CES1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL11253231 | 0.79 | KMT2A (0.43) | CES2CES1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9143119 | 0.76 | CES2 (0.47) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL6878186 | 0.76 | CES2 (0.47) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL6878184 | 0.76 | CES2 (0.47) | PTPN1CES2CES1SMN1; SMN2PKM | |
| SCHEMBL11329136 | 0.76 | SMN1; SMN2 (0.44) | PTPN1CES2CES1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0244195-A1 | 2-Vinylpenams and process | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1987-11-04 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |