Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560985 | 0.80 | L3MBTL1 (0.53) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL12300317 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HSD17B10HPGDL3MBTL1 | |
| SCHEMBL11261512 | 0.76 | MCL1 (0.54) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL17223747 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL24019095 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18883716 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10HPGDTSHR | |
| SCHEMBL21719084 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL11253301 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL11541935 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL7875134 | 0.73 | MAOB (0.42) | ALDH1A1SMN1; SMN2HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343808-A | Method of inhibiting sickling of sickle erythrocytes | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |