Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11361444 | 0.99 | MAPT (0.41) | MAPTNPSR1ACHEAPPLMNA | |
| SCHEMBL11249911 | 0.85 | BCHE (0.37) | KMT2A | |
| Hydrochloric Acid SCHEMBL11357746 | 0.84 | BCHE (0.37) | KMT2A | |
| SCHEMBL11246079 | 0.81 | MAPT (0.43) | MAPTNPSR1ACHEAPPLMNA | |
| SCHEMBL11251660 | 0.78 | BCHE (0.38) | ACHEPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11389008 | 0.77 | BCHE (0.38) | ACHEPOLBMEN1KMT2A | |
| SCHEMBL11040120 | 0.77 | DUSP10 (0.33) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11038147 | 0.77 | USP5 (0.35) | LMNATSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11038211 | 0.76 | PDE4A (0.41) | MAPTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11041821 | 0.76 | DUSP10 (0.33) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |