Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513901 | 0.88 | GAA (0.58) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL524175 | 0.83 | GAA (0.49) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11569683 | 0.81 | GAA (0.51) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13779473 | 0.81 | CA1 (0.50) | GAAKDM4EHPGDMAPTCA12 | |
| SCHEMBL8395371 | 0.81 | GAA (0.45) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL23796581 | 0.81 | CYP3A4 (0.56) | GAAKDM4EHPGDMAPTABL1 | |
| SCHEMBL2811429 | 0.80 | GAA (0.53) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1361427 | 0.80 | KDM4E (0.51) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL22081931 | 0.80 | ABL1 (0.49) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30689849 | 0.80 | KDM4E (0.56) | GAAKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344951-A | INSECTICIDES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-4159384-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4123455-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | disclosed |