Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513901 | 0.92 | GAA (0.58) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL17774713 | 0.84 | ALDH1A1 (0.64) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL11253706 | 0.81 | GAA (0.51) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL1271994 | 0.81 | KDM4E (0.61) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL11513909 | 0.81 | ALDH1A1 (0.47) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL30689849 | 0.80 | KDM4E (0.56) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL27201908 | 0.80 | KDM4E (0.56) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL22866262 | 0.79 | GAA (0.49) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL138319 | 0.79 | ALDH1A1 (0.55) | GAAALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL17774710 | 0.78 | ALDH1A1 (0.61) | GAAALDH1A1TDP1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159384-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4123455-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | disclosed |