Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855638 | 0.84 | GAA (0.53) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL23796581 | 0.84 | CYP3A4 (0.56) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL13779473 | 0.84 | CA1 (0.50) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL399550 | 0.82 | KDM4E (0.57) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL19100970 | 0.82 | CA1 (0.54) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL11767369 | 0.82 | ALDH1A1 (0.49) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL6739836 | 0.82 | CYP46A1 (0.44) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL3308973 | 0.81 | BCL2L1 (0.47) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL21817721 | 0.81 | XDH (0.47) | GAAPOLBCA12CA1CA2 | |
| SCHEMBL3310733 | 0.81 | KDR (0.43) | GAAPOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5000998-A | — | — | None | — | — | JP | disclosed |
| US-20230158158-A1 | PYRAZOLO QUINAZOLINE DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | UPPTHERA (KR) | 2023-05-25 | — | — | US | disclosed |
| US-10407376-B2 | Method to prepare phenolics from biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-09-10 | — | — | US | disclosed |
| US-10407376-B2 | Method to prepare phenolics from biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-09-10 | — | — | US | disclosed |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-12-07 | — | — | US | disclosed |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-12-07 | — | — | US | disclosed |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-12-07 | — | — | US | disclosed |
| EP-3245186-A1 | METHOD TO PREPARE PHENOLICS FROM BIOMASS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016114668-A1 | METHOD TO PREPARE PHENOLICS FROM BIOMASS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2016-07-21 | — | — | WO | disclosed |
| WO-2016114668-A1 | METHOD TO PREPARE PHENOLICS FROM BIOMASS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2016-07-21 | — | — | WO | disclosed |
| US-8003286-B2 | Photoreceptor for electrophotography | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20090104552-A1 | PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| US-5985913-A | GENE EXPRESSION AND CELL GROWTH FACTORS FOR BIOSYNTHESIS | OSI PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| JP-H05998-A | PRODUCTION OF 3,5-DI(ALPHA-METHYLBENZYL) SALICYLIC ACID DERIVATIVE AND ITS USE AS COLOR-DEVELOPING AGENT OF MULTI-VALENT METAL COMPOUND | MITSUI TOATSU CHEM INC | 1993-01-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407376-B2 | Method to prepare phenolics from biomass | FDPS, DNPH1, HPD | GAA 311/4885POLB 1330/4885CA12 3905/4885 |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | FDPS, DNPH1, HPD | GAA 311/4885POLB 1330/4885CA12 3905/4885 |
| US-20230158158-A1 | PYRAZOLO QUINAZOLINE DERIVATIVE COMPOUNDS INDUCING SELECTIVE DEGRADATION OF PLK1 | PLK1, BUB1, BUB1B | GAA 2885/4885POLB 650/4885CA12 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.