Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019866 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL291121 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1MAPTGPR3MCL1 | |
| SCHEMBL150108 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29142014 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1MAPTGPR3MCL1 | |
| Hydrochloric Acid SCHEMBL8533214 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1MAPTGPR3MCL1 | |
| SCHEMBL4696033 | 0.69 | GPR3 (0.68) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 | |
| SCHEMBL29374932 | 0.69 | GPR3 (0.68) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 | |
| SCHEMBL30515127 | 0.69 | GPR3 (0.68) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 | |
| SCHEMBL9160474 | 0.69 | GPR3 (0.68) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 | |
| SCHEMBL36332 | 0.69 | GPR3 (0.68) | KDM4EALDH1A1MAPTHCRTR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |