Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8533214 | 0.98 | KDM4E (0.54) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| Hydrochloric Acid SCHEMBL29142014 | 0.98 | KDM4E (0.54) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL29019866 | 0.87 | KDM4E (0.49) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL28563540 | 0.75 | MAPT (0.60) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL30987223 | 0.75 | MAPT (0.60) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL8804430 | 0.73 | CYP2A6 (0.42) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL8388159 | 0.73 | KDM4E (0.42) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11253709 | 0.72 | KDM4E (0.46) | KDM4EMAPTALDH1A1GPR3LOXL2 | |
| SCHEMBL4204967 | 0.71 | MAPT (0.56) | KDM4EMAPTALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11654916 | 0.71 | MAPT (0.56) | KDM4EMAPTALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117517501-A | Ziprasidone hydrochloride, synthesis intermediate thereof and liquid chromatography detection method of impurities | 湖南省湘中制药有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-116836095-A | Method for preparing 2,2' -dithiobis (benzonitrile) | 常州大学 | 2023-10-03 | — | — | CN | claimed |
| CN-116003343-A | New resolution method of lurasidone hydrochloride intermediate | 辰欣药业股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-113009042-B | 3- (1-piperazinyl) -1,2-benzisothiazole hydrochloride and analysis and detection method of related substances thereof | 海南鑫开源医药科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113292510-B | Benzisothiazole compound for inhibiting hypoxia inducible factor 2 activity, preparation method and application thereof | 中国药科大学 | 2022-08-26 | — | — | CN | claimed |
| CN-113292510-A | Benzisothiazole compound for inhibiting hypoxia inducible factor 2 activity, preparation method and application thereof | 中国药科大学 | 2021-08-24 | — | — | CN | claimed |
| CN-112920135-A | Dimer impurity in ziprasidone hydrochloride raw material and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-109645002-A | Synergetic pesticide composition containing D- limonene | 广东中迅农科股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| US-8664404-B2 | Method for producing 3-halo-1,2-benzisothiazoles | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2014-03-04 | — | — | US | claimed |
| EP-0846692-B1 | Process for preparation of 3-chlorobenzisothiazoles | BAYER AG (DE) | 2001-10-04 | — | — | EP | claimed |
| US-5883258-A | Process for preparing 3-chlorobenzisothiazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | claimed |
| JP-5017457-A | — | — | None | — | — | JP | disclosed |
| JP-10168070-A | — | — | None | — | — | JP | disclosed |
| CN-116836095-B | Method for preparing 2,2' -dithiobis (benzonitrile) | 常州大学 | 2025-07-11 | — | — | CN | disclosed |
| CN-116283820-B | Preparation method of 3-halogeno-1, 2-benzisothiazole | 寿光新泰精细化工有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-4140693-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4110449-A | ANTIINFLAMMATORY, SEDATIVE, MUSCLE RELAXANT | E. R. SQUIBB & SONS, INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4108860-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4104388-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-4104387-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-08-01 | — | — | US | disclosed |