Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11919881 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11252500 | 0.78 | AKR1B1 (0.53) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24593 | 0.78 | ALPG (0.46) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11249842 | 0.76 | KDM4E (0.41) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11249851 | 0.76 | KDM4E (0.41) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31309445 | 0.76 | ALPG (0.45) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17383700 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1PSDSMN1; SMN2NPC1 | |
| SCHEMBL11250685 | 0.75 | ALPG (0.42) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11250680 | 0.75 | ALPG (0.42) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11263149 | 0.74 | ALPG (0.44) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341780-A | Substituted pyrido [1,2-a] pyrimidines useful as anti-allergic, anti-ulcer and anti-diabetic agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-07-27 | — | — | US | disclosed |
| US-4310526-A | Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-01-12 | — | — | US | disclosed |