Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540395 | 0.86 | ALPG (0.40) | AKR1B1ALPGKDM4EBRD4CTDSP1 | |
| SCHEMBL24593 | 0.81 | ALPG (0.46) | AKR1B1ALPGKDM4EBRD4TDP1 | |
| SCHEMBL31309445 | 0.79 | ALPG (0.45) | AKR1B1ALPGKDM4EBRD4TDP1 | |
| SCHEMBL11254686 | 0.78 | P2RX3 (0.46) | AKR1B1ALPGKDM4ECTDSP1TDP1 | |
| SCHEMBL11254681 | 0.78 | P2RX3 (0.46) | AKR1B1ALPGKDM4ECTDSP1TDP1 | |
| SCHEMBL11254178 | 0.78 | ALPG (0.50) | AKR1B1ALPGKDM4EBRD4TDP1 | |
| SCHEMBL11262214 | 0.77 | ALPG (0.45) | AKR1B1ALPGKDM4ECTDSP1ALDH1A1 | |
| SCHEMBL11262197 | 0.77 | ALPG (0.45) | AKR1B1ALPGKDM4ECTDSP1ALDH1A1 | |
| SCHEMBL11162079 | 0.76 | KDM4E (0.47) | AKR1B1ALPGKDM4ETDP1ALDH1A1 | |
| SCHEMBL11248463 | 0.76 | AKR1B1 (0.52) | AKR1B1ALPGTP53SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341780-A | Substituted pyrido [1,2-a] pyrimidines useful as anti-allergic, anti-ulcer and anti-diabetic agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-07-27 | — | — | US | disclosed |
| US-4310526-A | Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-01-12 | — | — | US | disclosed |