Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256903 | 0.91 | ABCB1 (0.60) | ABCB1DRD2HRH3BCHE | |
| SCHEMBL11258366 | 0.89 | HRH3 (0.50) | ABCB1DRD2ALDH1A1HRH3LTA4H | |
| SCHEMBL11259036 | 0.89 | LTA4H (0.55) | ABCB1ALDH1A1LTA4H | |
| SCHEMBL11260267 | 0.89 | ABCB1 (0.48) | ABCB1DRD2ALDH1A1HRH3LTA4H | |
| SCHEMBL11247964 | 0.89 | ABCB1 (0.54) | ABCB1DRD2LTA4HBCHE | |
| SCHEMBL11246818 | 0.88 | CYP2D6 (0.48) | ABCB1DRD2ALDH1A1POLBHRH3 | |
| SCHEMBL11252854 | 0.87 | KCNH2 (0.53) | ALDH1A1POLBHRH3LTA4H | |
| SCHEMBL11252400 | 0.86 | MEN1 (0.58) | ABCB1DRD2HRH3LTA4H | |
| SCHEMBL11250630 | 0.84 | KCNH2 (0.53) | ABCB1DRD2HRH3LTA4H | |
| SCHEMBL11248501 | 0.84 | ABCB1 (0.66) | ABCB1DRD2ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |