Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259036 | 0.92 | LTA4H (0.55) | LTA4HABCB1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11250630 | 0.91 | KCNH2 (0.53) | HRH3LTA4HABCB1L3MBTL1KDM4E | |
| SCHEMBL11260526 | 0.91 | KDM4E (0.50) | HRH3LTA4HABCB1L3MBTL1KDM4E | |
| SCHEMBL11252854 | 0.90 | KCNH2 (0.53) | HRH3LTA4HL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11260267 | 0.89 | ABCB1 (0.48) | HRH3LTA4HABCB1L3MBTL1KDM4E | |
| SCHEMBL11254251 | 0.89 | ABCB1 (0.59) | HRH3LTA4HABCB1ALDH1A1DRD2 | |
| SCHEMBL11252400 | 0.89 | MEN1 (0.58) | HRH3LTA4HABCB1L3MBTL1KDM4E | |
| SCHEMBL11246818 | 0.88 | CYP2D6 (0.48) | HRH3ABCB1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11256008 | 0.87 | KDM4E (0.52) | HRH3LTA4HABCB1L3MBTL1KDM4E | |
| SCHEMBL11254264 | 0.85 | LTA4H (0.64) | LTA4HABCB1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |