SCHEMBL11254405

SCHEMBL11254405

COc1ccc(C)cc1.c1cc2cc-2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.68
ABL1 P00519 2/20 0.64
ABCB1 P08183 2/20 0.64
BCR P11274 2/20 0.64
CYP1A1 P04798 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2E1 P05181 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2C8 P10632 2/20 0.61
CYP2D6 P10635 2/20 0.61
CYP2A6 P11509 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP4B1 P13584 2/20 0.61
CYP2B6 P20813 2/20 0.61
CYP3A5 P20815 2/20 0.61
CYP2A7 P20853 2/20 0.61
CYP3A7 P24462 2/20 0.61
CYP2F1 P24903 2/20 0.61
CYP2C18 P33260 2/20 0.61
CYP2C19 P33261 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12871359 0.96 ABL1 (0.71) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL1180429 0.86 ABL1 (0.83) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL20022136 0.85 ABL1 (0.69) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL20022108 0.85 ABL1 (0.69) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL12871361 0.85 ABL1 (0.63) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL20022095 0.84 ABL1 (0.72) ACHEABL1ABCB1BCRCYP1A1
Benzene SCHEMBL11242974 0.83 ACHE (0.88) ACHERELANPC1RAB9AKMT2A
SCHEMBL1047258 0.83 ALKBH3 (0.65) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL25873212 0.83 ALKBH3 (0.65) ACHEABL1ABCB1BCRCYP1A1
SCHEMBL1133171 0.83 ABL1 (0.66) ACHEABL1ABCB1BCRCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed