Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257083 | 0.89 | POLB (0.43) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11273329 | 0.89 | POLB (0.38) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11259565 | 0.89 | POLB (0.38) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11270710 | 0.85 | CYP11B1 (0.42) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11256840 | 0.84 | CYP11B1 (0.48) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11255600 | 0.83 | CYP11B1 (0.40) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11271165 | 0.82 | CYP11B1 (0.48) | CYP11B1CYP11B2KMT2ACYP19A1 | |
| SCHEMBL11265549 | 0.82 | ADRA2C (0.41) | CYP11B1CYP19A1 | |
| SCHEMBL11262095 | 0.82 | POLB (0.39) | POLBCTDSP1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11253666 | 0.82 | POLB (0.44) | POLBCTDSP1TDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |