Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268945 | 0.90 | ADRA2C (0.42) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11258654 | 0.90 | HMOX1 (0.42) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11259885 | 0.90 | CYP2C9 (0.40) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11261952 | 0.90 | FNTA (0.40) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11257609 | 0.89 | FNTA (0.39) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11259912 | 0.88 | HMOX1 (0.41) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11269111 | 0.86 | ADRA2C (0.41) | ADRA2CCYP2C9PGRCHRM2CYP3A4 | |
| SCHEMBL11273444 | 0.86 | HMOX1 (0.37) | ADRA2CCYP17A1LMNACYP19A1HMOX1 | |
| SCHEMBL11266730 | 0.84 | HMOX1 (0.49) | CYP19A1HMOX1CYP11B1 | |
| SCHEMBL11254200 | 0.84 | ADRA2C (0.46) | ADRA2CCYP2C9PGRCHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |