Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585953 | 0.88 | SOS1 (0.37) | SOS1KDM4EALDH1A1GLAGAA | |
| SCHEMBL18000514 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL5500439 | 0.75 | NNMT (0.41) | KDM4EHTTLMNANNMTPARP10 | |
| SCHEMBL3394127 | 0.73 | TERT (0.35) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL5191450 | 0.73 | CYP1A2 (0.41) | KDM4EALDH1A1HPGDHTTLMNA | |
| SCHEMBL1697089 | 0.72 | LCK (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28143231 | 0.70 | PARP10 (0.48) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL13254935 | 0.69 | NNMT (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL15190459 | 0.69 | NNMT (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL3339070 | 0.69 | PARP10 (0.45) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284157-A1 | Quinolines useful in treating cardiovascular disease | Wyeth (US) | 2011-02-16 | — | — | EP | disclosed |