Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259377 | 0.91 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11259257 | 0.90 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11247958 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11388178 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11390903 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL7061952 | 0.84 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11380096 | 0.82 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11256983 | 0.82 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1GAACYP1A2TSHR | |
| SCHEMBL11551611 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL11252362 | 0.80 | CASP1 (0.48) | ALDH1A1GAACYP1A2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |