Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332154 | 0.82 | KMT2A (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4200404 | 0.79 | ALDH1A1 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL109451 | 0.77 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4200358 | 0.77 | MAPT (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5071141 | 0.75 | CA12 (0.47) | CA12CA1CA2CA9CA14 | |
| Hydrazine SCHEMBL10771056 | 0.73 | CA12 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL11082868 | 0.73 | GABRA1 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9097558 | 0.73 | CA1 (0.44) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4867454 | 0.73 | GABRA1 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL557689 | 0.73 | ALDH1A1 (0.49) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052299-A1 | 2-Oxoazetidine derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1982-05-26 | — | — | EP | claimed |