Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261999 | 0.95 | PTGS2 (0.47) | PTGS2PTGS1L3MBTL1ABCB1MAPT | |
| SCHEMBL11152420 | 0.93 | PTGS2 (0.43) | PTGS2PTGS1L3MBTL1ABCB1MAPT | |
| SCHEMBL11263983 | 0.92 | PTGS2 (0.45) | PTGS2PTGS1L3MBTL1ABCB1MAPT | |
| SCHEMBL11271305 | 0.88 | PTGS2 (0.48) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL11256561 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1ABCB1MAPTCXCR1 | |
| SCHEMBL11261401 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1ABCB1MAPTCXCR1 | |
| SCHEMBL11258342 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL11274096 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL11171930 | 0.85 | L3MBTL1 (0.39) | PTGS2PTGS1L3MBTL1ABCB1MAPT | |
| SCHEMBL11263518 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1ABCB1MAPTCXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |