Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255656 | 1.00 | LMNA (0.47) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL11247340 | 0.83 | LMNA (0.52) | LMNAALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8024978 | 0.83 | LMNA (0.52) | LMNAALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8024983 | 0.83 | LMNA (0.52) | LMNAALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL11251009 | 0.81 | NPC1 (0.50) | ALDH1A1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11251013 | 0.81 | NPC1 (0.50) | ALDH1A1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8819049 | 0.76 | TSHR (0.47) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8539430 | 0.76 | TSHR (0.47) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL563939 | 0.76 | TSHR (0.47) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27467526 | 0.75 | LMNA (0.47) | LMNAMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |