Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | TDO2 | P48775 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265968 | 0.84 | ALDH1A1 (0.44) | CYP1A2CYP2A6TDO2L3MBTL1NPSR1 | |
| SCHEMBL30631719 | 0.81 | PLG (0.54) | TDO2HTR2BHTR5AL3MBTL1NPSR1 | |
| SCHEMBL23095358 | 0.79 | ALDH1A1 (0.48) | CYP1A2CYP2A6L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL26185762 | 0.78 | TDO2 (0.42) | TDO2HTR2BHTR5AL3MBTL1NPSR1 | |
| SCHEMBL11976465 | 0.78 | NQO2 (0.49) | CYP1A2CYP2A6TDO2HTR2BHTR5A | |
| SCHEMBL13169304 | 0.78 | PLG (0.51) | TDO2HTR2BHTR5AL3MBTL1NPSR1 | |
| SCHEMBL3146190 | 0.78 | TDO2 (0.47) | CYP1A2TDO2HTR2BHTR5AL3MBTL1 | |
| SCHEMBL15712262 | 0.78 | ALDH1A1 (0.48) | TDO2HTR2BHTR5AL3MBTL1NPSR1 | |
| SCHEMBL11259942 | 0.77 | TDO2 (0.44) | TDO2HTR2BHTR5AL3MBTL1NPSR1 | |
| SCHEMBL11100168 | 0.77 | PDE3B (0.53) | CYP1A2TDO2HTR2BHTR5AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |