Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228219 | 0.70 | KCNH2 (0.46) | CCNCCDK8 | |
| SCHEMBL11239728 | 0.69 | PDE4A (0.38) | CCNCCDK8 | |
| SCHEMBL11325503 | 0.69 | CCNC (0.38) | CCNCCDK8 | |
| SCHEMBL19441232 | 0.64 | CYP2C19 (0.49) | CCNCCDK8 | |
| SCHEMBL19601134 | 0.64 | CCNC (0.54) | CCNCCDK8 | |
| SCHEMBL12811202 | 0.62 | CCNC (0.45) | CCNCCDK8 | |
| SCHEMBL14927060 | 0.61 | CCNC (0.51) | CCNCCDK8 | |
| SCHEMBL877689 | 0.60 | CYP2E1 (0.48) | CCNCCDK8 | |
| Bromide SCHEMBL29018736 | 0.60 | CCNC (0.50) | CCNCCDK8 | |
| SCHEMBL11398844 | 0.59 | CCNC (0.40) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337253-A | 4,5-Dihydro-2-methyl-6-(4-pyridinyl)-3(2H)-pyridazinone and its use as a cardiotonic | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |