Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259036 | 0.89 | LTA4H (0.55) | KDM4EALDH1A1LTA4HL3MBTL1MEN1 | |
| SCHEMBL11250630 | 0.88 | KCNH2 (0.53) | KDM4ELTA4HL3MBTL1ABCB1HRH3 | |
| SCHEMBL11258366 | 0.87 | HRH3 (0.50) | KDM4EALDH1A1LTA4HL3MBTL1MEN1 | |
| SCHEMBL11252400 | 0.86 | MEN1 (0.58) | KDM4ELTA4HL3MBTL1MEN1KMT2A | |
| SCHEMBL11261087 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1LTA4HL3MBTL1MEN1 | |
| SCHEMBL11258518 | 0.83 | ABCB1 (0.53) | KDM4EL3MBTL1MEN1KMT2AABCB1 | |
| SCHEMBL11252854 | 0.83 | KCNH2 (0.53) | KDM4EALDH1A1LTA4HL3MBTL1MEN1 | |
| SCHEMBL11260267 | 0.83 | ABCB1 (0.48) | KDM4EALDH1A1LTA4HL3MBTL1MEN1 | |
| SCHEMBL11254264 | 0.83 | LTA4H (0.64) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL11259471 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |