Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.46 |
| ▸ | PLD2 | O14939 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033261 | 0.87 | OPRM1 (0.60) | OPRM1PLD1PLD2OPRD1OPRK1 | |
| SCHEMBL11217080 | 0.85 | PLD2 (0.50) | OPRM1PLD1PLD2OPRD1OPRK1 | |
| SCHEMBL11199327 | 0.84 | PLD1 (0.51) | OPRM1PLD1PLD2OPRD1OPRL1 | |
| SCHEMBL11199325 | 0.84 | PLD1 (0.51) | OPRM1PLD1PLD2OPRD1OPRL1 | |
| SCHEMBL11199321 | 0.84 | PLD1 (0.51) | OPRM1PLD1PLD2OPRD1OPRL1 | |
| SCHEMBL11206487 | 0.84 | PLD1 (0.51) | OPRM1PLD1PLD2OPRD1OPRL1 | |
| SCHEMBL11221635 | 0.79 | PLD1 (0.51) | OPRM1PLD1PLD2OPRD1OPRK1 | |
| SCHEMBL11221627 | 0.79 | PLD2 (0.43) | OPRM1PLD1PLD2OPRK1 | |
| SCHEMBL11031960 | 0.78 | OPRM1 (0.62) | OPRM1PLD1PLD2OPRD1OPRK1 | |
| SCHEMBL11250457 | 0.77 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092391-A2 | Novel piperidine derivatives and pharmaceutical compositions containing same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-10-26 | — | — | EP | disclosed |