Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996540 | 0.82 | KMT2A (0.44) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL31119425 | 0.78 | L3MBTL1 (0.42) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL1979476 | 0.78 | KMT2A (0.46) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL11767521 | 0.78 | L3MBTL1 (0.42) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL31119438 | 0.75 | KMT2A (0.40) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL7412921 | 0.75 | KMT2A (0.40) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL10116257 | 0.75 | KMT2A (0.40) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL3626864 | 0.73 | LMNA (0.43) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL3674235 | 0.73 | LMNA (0.43) | KMT2AL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL27820534 | 0.73 | LMNA (0.43) | KMT2AL3MBTL1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366160-A | ANALGESICS | HOFFMANN-LA ROCHE INC. (US) | 1982-12-28 | — | — | US | disclosed |