Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792565 | 0.80 | CA1 (0.50) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL95164 | 0.80 | KDM4E (1.00) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL11758440 | 0.79 | ALDH1A1 (0.41) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL11249261 | 0.76 | KDM4E (0.66) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20183947 | 0.75 | CYP3A4 (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30987784 | 0.74 | KDM4E (0.86) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL17367952 | 0.74 | KDM4E (0.86) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9880008 | 0.72 | KDM4E (0.77) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL21891255 | 0.72 | KDM4E (0.83) | MAPTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL11472392 | 0.72 | KDM4E (0.71) | MAPTMEN1KMT2AKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317768-A | A PHENYL DIESTER OF 3,5-DICARBOXY-1,4-DIHYDROPYRIDINE | LABAZ (FR) | 1982-03-02 | — | — | US | disclosed |
| US-4239893-A | STABILIZERS FOR VINYL RESINS | LABAZ (FR) | 1980-12-16 | — | — | US | disclosed |