Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367952 | 0.93 | KDM4E (0.86) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL30987784 | 0.93 | KDM4E (0.86) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL8037231 | 0.93 | KDM4E (0.86) | KDM4EMEN1KMT2AMAPTALOX15 | |
| Acetic Acid SCHEMBL28855875 | 0.91 | KDM4E (0.83) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL21891255 | 0.91 | KDM4E (0.83) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL434624 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL28855873 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL14963234 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL14957474 | 0.89 | KDM4E (0.80) | KDM4EMEN1KMT2AMAPTALOX15 | |
| SCHEMBL9880008 | 0.87 | KDM4E (0.77) | KDM4EMEN1KMT2AMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079942-A | Method for organically catalyzing dynamic resolution of oxaspirorenone carbon-oxygen bond hydrogenolysis | — | 2026-05-26 | — | — | CN | claimed |
| CN-122010747-A | Photochemical synthesis method of fluorine-containing tertiary amine | 贵州医科大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122011026-A | Asymmetric bidentate phosphine ligand and synthesis method thereof | 淮北师范大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4735459-A1 | METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4705311-A1 | PROTECTING-GROUP-FREE CARBOHYDRATE SYNTHESIS USING BENCH-STABLE HETEROARYL GLYCOSYL SULFIDES AS DONORS | National University of Singapore (SG) | 2026-03-11 | — | — | EP | claimed |
| US-12494072-B2 | Maturity classification of stained reticulocytes using optical microscopy | Siemens Healthineers Ag (DE) | 2025-12-09 | — | — | US | claimed |
| US-12435049-B2 | Synthesis of vinylic protected alcohol intermediates | AMGEN INC. (US) | 2025-10-07 | — | — | US | claimed |
| US-12410149-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | NORTHWESTERN UNIVERSITY (US) | 2025-09-09 | — | — | US | claimed |
| US-20250257095-A1 | METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2025-08-14 | — | — | US | claimed |
| CN-120158115-A | Surface modified pre-dispersed pigment and modification method | 安徽和盛新材料科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| US-20080064877-A2 | PROCESS FOR THE PREPARATION OF ROSIGLITAZONE | MEDICHEM S.A. (ES) | 2008-03-13 | — | — | US | claimed |
| US-20070225501-A1 | Process for the Preparation of Rosiglitazone | MEDICHEM S.A. (ES) | 2007-09-27 | — | — | US | claimed |
| EP-1621576-B1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM & HAAS (US) | 2007-02-14 | — | — | EP | claimed |
| EP-1745043-A1 | PROCESS FOR THE PREPARATION OF ROSIGLITAZONE | Medichem S.A. (ES) | 2007-01-24 | — | — | EP | claimed |
| US-20060025503-A1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | PMC CINCINNATI, INC. | 2006-02-02 | — | — | US | claimed |
| EP-1621576-A1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | Rohm and Haas Company (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2005108394-A1 | PROCESS FOR THE PREPARATION OF ROSIGLITAZONE | MEDICHEM S.A. (ES) | 2005-11-17 | — | — | WO | claimed |
| EP-0362012-B1 | Stabiliser compositions for halogenated polymers containing beta-diketone, hydrotalcite and dihydropyridine, and polymers stabilized therewith | ATOCHEM ELF SA (FR) | 1993-12-29 | — | — | EP | claimed |
| US-4769382-A | Preparation for preventing and treatment of skin radiation burn lesions | INSTITUT ORGANISCHESKOGO SINTEZA LENINGRADSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT (SU) | 1988-09-06 | — | — | US | claimed |
| EP-0005678-B1 | COMPOSITIONS CONTAINING THERMALLY STABILIZED PVC | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-11-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225501-A1 | Process for the Preparation of Rosiglitazone | PPARD, PPARG, GPR119 | KDM4E 907/4885MEN1 4475/4885KMT2A 3024/4885 |
| US-12410149-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | TYR, ME1, PNPO | KDM4E 2241/4885MEN1 1059/4885KMT2A 3672/4885 |
| US-12435049-B2 | Synthesis of vinylic protected alcohol intermediates | MCL1, BCL2A1, BAK1 | KDM4E 1843/4885MEN1 43/4885KMT2A 2033/4885 |
| US-20080064877-A2 | PROCESS FOR THE PREPARATION OF ROSIGLITAZONE | PPARD, PPARG, GPR119 | KDM4E 1063/4885MEN1 4442/4885KMT2A 3309/4885 |
| US-20250257095-A1 | METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE | PTMS, CTH, CISD1 | KDM4E 4642/4885MEN1 4662/4885KMT2A 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.