Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203537 | 0.87 | NPSR1 (0.69) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL11267022 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11205782 | 0.85 | NPSR1 (0.52) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL9174433 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11206166 | 0.83 | NPSR1 (0.50) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL6824607 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MEN1KMT2ACASP3 | |
| SCHEMBL11200099 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL26309124 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL29506649 | 0.81 | POLB (0.65) | ALDH1A1L3MBTL1MEN1KMT2ACASP3 | |
| SCHEMBL1547024 | 0.81 | POLB (0.65) | ALDH1A1L3MBTL1MEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31103-E | HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS | RAYCHEM CORPORATION (US) | 1982-12-14 | — | — | US | claimed |
| US-4121001-A | IMIDE OR DIIMIDE | RAYCHEM CORPORATION (US) | 1978-10-17 | — | — | US | claimed |
| US-RE31103-E | HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS | RAYCHEM CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |
| US-4121001-A | IMIDE OR DIIMIDE | RAYCHEM CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |