SCHEMBL11267022

SCHEMBL11267022

C=CCN1C(=O)c2ccc(C(=O)OC=C)cc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
CASP3 P42574 1/20 0.47
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174433 0.85 ALDH1A1 (0.54) ALDH1A1L3MBTL1CASP3LMNAPOLB
SCHEMBL11256702 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1CASP3LMNAPOLB
SCHEMBL6824607 0.84 ALDH1A1 (0.59) ALDH1A1L3MBTL1CASP3POLBMEN1
SCHEMBL1547024 0.82 POLB (0.65) ALDH1A1L3MBTL1CASP3POLBMEN1
SCHEMBL29506649 0.82 POLB (0.65) ALDH1A1L3MBTL1CASP3POLBMEN1
SCHEMBL9177192 0.82 ALDH1A1 (0.54) ALDH1A1L3MBTL1CASP3LMNAPOLB
SCHEMBL9175052 0.82 ALDH1A1 (0.51) ALDH1A1L3MBTL1CASP3LMNAPOLB
Hydrochloric Acid SCHEMBL11258671 0.81 POLB (0.63) ALDH1A1L3MBTL1CASP3POLBMEN1
SCHEMBL1547317 0.81 L3MBTL1 (0.53) ALDH1A1L3MBTL1CASP3POLBMEN1
SCHEMBL9172355 0.80 ALDH1A1 (0.49) ALDH1A1L3MBTL1CASP3LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31103-E HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS RAYCHEM CORPORATION (US) 1982-12-14 US disclosed
US-4121001-A IMIDE OR DIIMIDE RAYCHEM CORPORATION (US) 1978-10-17 US disclosed