Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088617 | 0.89 | HTT (0.43) | PTGS1PTGS2HTTALDH1A1KDM4E | |
| SCHEMBL11436265 | 0.82 | MT-CO2 (0.39) | MT-CO2GPR139 | |
| SCHEMBL11266270 | 0.78 | KDM4E (0.43) | MT-CO2ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL11267327 | 0.78 | ALPG (0.49) | MT-CO2ALDH1A1KDM4EHPGDTBXAS1 | |
| SCHEMBL11266029 | 0.75 | MT-CO2 (0.43) | MT-CO2TBXAS1PTAFRALPG | |
| SCHEMBL11429362 | 0.75 | ALPG (0.65) | TBXAS1PTAFRALPG | |
| SCHEMBL11080644 | 0.75 | KDM4E (0.48) | ALDH1A1KDM4ECYP1A2HPGDTBXAS1 | |
| SCHEMBL11269248 | 0.75 | ALPG (0.48) | TBXAS1PTAFRALPG | |
| SCHEMBL11080513 | 0.75 | ALPG (0.48) | TBXAS1PTAFRALPG | |
| SCHEMBL11081254 | 0.75 | ALPG (0.48) | TBXAS1PTAFRALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011142-B1 | PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | claimed |
| EP-0011142-B1 | PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |