Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.64 |
| ▸ | HTR2A | P28223 | 12/20 | 0.64 |
| ▸ | HTR7 | P34969 | 3/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220455 | 0.93 | DRD2 (0.63) | DRD2HTR2AHTR7KCNH2HTR1A | |
| Fumaric Acid SCHEMBL10634678 | 0.90 | DRD2 (0.63) | DRD2HTR2AHTR7KCNH2HTR1A | |
| Fumaric Acid SCHEMBL10634692 | 0.90 | DRD2 (0.63) | DRD2HTR2AHTR7KCNH2HTR1A | |
| SCHEMBL11239226 | 0.88 | DRD2 (0.68) | DRD2HTR2AHTR7KCNH2HTR1A | |
| SCHEMBL84566 | 0.86 | DRD2 (0.70) | DRD2HTR2AHTR7KCNH2HTR1A | |
| Fumaric Acid SCHEMBL10637261 | 0.84 | DRD2 (0.60) | DRD2HTR2AHTR7KCNH2HTR1A | |
| Fumaric Acid SCHEMBL10637273 | 0.84 | DRD2 (0.60) | DRD2HTR2AHTR7KCNH2HTR1A | |
| SCHEMBL85060 | 0.84 | DRD2 (0.61) | DRD2HTR2AHTR7KCNH2HTR1A | |
| SCHEMBL22048329 | 0.83 | DRD2 (0.57) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL21678218 | 0.83 | DRD2 (0.58) | DRD2HTR2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355037-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS (US) | 1982-10-19 | — | — | US | claimed |