Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.70 |
| ▸ | HTR2A | P28223 | 12/20 | 0.62 |
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 9/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85060 | 0.92 | DRD2 (0.61) | DRD2SLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL21678218 | 0.86 | DRD2 (0.58) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL22048329 | 0.86 | DRD2 (0.57) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL24279786 | 0.86 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL11239226 | 0.86 | DRD2 (0.68) | DRD2SLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL85001 | 0.86 | DRD2 (0.57) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL11257136 | 0.86 | DRD2 (0.64) | DRD2HTR2AHTR7HTR1AKCNH2 | |
| Hydrochloric Acid SCHEMBL21987945 | 0.85 | DRD2 (0.56) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL10637706 | 0.84 | DRD2 (0.55) | DRD2HTR2AHTR7HTR1A | |
| SCHEMBL23595619 | 0.84 | DRD2 (0.56) | DRD2SLC6A4HTR2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129410-B2 | Sleep maintenance insomnia; circadian rhythm abnormalities; side effect reduction | HYPNION, INC. (US) | 2012-03-06 | — | — | US | disclosed |