Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007022 | 0.77 | TSHR (0.48) | TTRMAOBPBRM1PSMB8PSMB5 | |
| SCHEMBL11257620 | 0.75 | TSHR (0.43) | TTRMAOBPBRM1PSMB8PSMB5 | |
| SCHEMBL11622080 | 0.74 | MAOB (0.56) | TTRMAOBPSMB8PSMB5MAOA | |
| SCHEMBL11538924 | 0.73 | CES1 (0.42) | TTRMAOBMAOAALOX15ALOX12 | |
| SCHEMBL28990332 | 0.73 | TTR (0.41) | TTRMAOBPSMB8PSMB5MAOA | |
| SCHEMBL28577211 | 0.73 | TTR (0.41) | TTRMAOBPSMB8PSMB5MAOA | |
| SCHEMBL11253212 | 0.73 | MAOB (0.72) | MAOBMAOAADORA2B | |
| Hydrochloric Acid SCHEMBL11256800 | 0.72 | MAOB (0.70) | MAOBMAOAADORA2B | |
| SCHEMBL30307601 | 0.71 | PTPN1 (0.62) | TTRMAOBMAOA | |
| SCHEMBL20793835 | 0.70 | NR4A2 (0.54) | PSMB8PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |