Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567067 | 0.79 | CES1 (0.42) | CYP1A2CYP2A6MAOBPTPN1ALOX15 | |
| SCHEMBL28990332 | 0.79 | TTR (0.41) | TTRCYP1A2CYP2A6MAOBMAOA | |
| SCHEMBL11538924 | 0.79 | CES1 (0.42) | TTRCYP1A2CYP2A6MAOBMAOA | |
| SCHEMBL30307601 | 0.76 | PTPN1 (0.62) | TTRMAOBMAOAPTPN1MEN1 | |
| SCHEMBL11622080 | 0.76 | MAOB (0.56) | TTRMAOBMAOAPIK3CAALOX15 | |
| SCHEMBL28569270 | 0.74 | POLB (0.62) | CYP1A2PTPN1ALOX15MEN1POLB | |
| SCHEMBL31037935 | 0.74 | POLB (0.62) | CYP1A2PTPN1ALOX15MEN1POLB | |
| SCHEMBL28477789 | 0.73 | TDP1 (0.47) | MAOAMEN1POLBKMT2A | |
| SCHEMBL11257622 | 0.73 | TTR (0.43) | TTRMAOBMAOAPIK3CAALOX15 | |
| SCHEMBL8815383 | 0.72 | TTR (0.65) | TTRCYP1A2CYP2A6MAOAAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899150-A | Synthetic method and application of 3-trifluoromethyl quinoline compound | 遵义医科大学 | 2025-04-29 | — | — | CN | disclosed |
| CN-118406075-A | Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof | 遵义医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114560838-B | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-112898256-B | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113149948-B | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114560838-A | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-110003231-B | 1, 1-spironorbornane-pyrano [4, 3-b ] chromone compound and preparation method and application thereof | 遵义医科大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-113149948-A | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-112898256-A | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2021-06-04 | — | — | CN | disclosed |