Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 3/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257620 | 0.87 | TSHR (0.43) | TSHRALDH1A1MAOBTTRPSMB8 | |
| SCHEMBL20793835 | 0.81 | NR4A2 (0.54) | TSHRALDH1A1PSMB8PSMB5KDM4E | |
| SCHEMBL29853275 | 0.79 | MAOB (0.49) | ALDH1A1MAOBKDM4EMEN1KMT2A | |
| SCHEMBL2729243 | 0.79 | MAOB (0.49) | ALDH1A1MAOBKDM4EMEN1KMT2A | |
| SCHEMBL4222147 | 0.79 | ALB (0.47) | ALDH1A1MAOBTTRPSMB8PSMB5 | |
| SCHEMBL23360189 | 0.79 | MCL1 (0.51) | ALDH1A1MAOBPSMB8PSMB5KDM4E | |
| SCHEMBL7568303 | 0.78 | SMN1; SMN2 (0.55) | TTRPSMB8PSMB5KDM4EMAPT | |
| SCHEMBL11257622 | 0.77 | TTR (0.43) | MAOBTTRPSMB8PSMB5KDM4E | |
| SCHEMBL7948373 | 0.75 | ALDH1A1 (0.51) | TSHRALDH1A1MAOBPSMB8PSMB5 | |
| SCHEMBL20765804 | 0.74 | PSMB5 (0.46) | TSHRMAOBTTRPSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |