Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054808 | 0.88 | MEN1 (0.43) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11051039 | 0.87 | HTT (0.49) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11050083 | 0.85 | MAPK1 (0.55) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11260410 | 0.85 | SMN1; SMN2 (0.48) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11265410 | 0.84 | KMT2A (0.56) | MAPK1MEN1KMT2ARAB9APOLB | |
| SCHEMBL11054793 | 0.83 | NPC1 (0.44) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11578638 | 0.81 | KMT2A (0.40) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11259425 | 0.80 | POLB (0.43) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11052110 | 0.80 | MEN1 (0.55) | MAPK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11250182 | 0.78 | NPC1 (0.40) | MAPK1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |