Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052077 | 0.88 | MEN1 (0.74) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11052475 | 0.87 | POLB (0.61) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11052110 | 0.85 | MEN1 (0.55) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11260410 | 0.85 | SMN1; SMN2 (0.48) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11260929 | 0.85 | KMT2A (0.50) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11257947 | 0.84 | MAPK1 (0.43) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11053827 | 0.83 | MAPK1 (0.54) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11052870 | 0.81 | PDK1 (0.51) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11254460 | 0.81 | HTT (0.44) | KMT2AMEN1MAPK1POLBLMNA | |
| SCHEMBL11253044 | 0.80 | MAPT (0.56) | MAPK1POLBLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |