SCHEMBL11258009

SCHEMBL11258009

Fc1ccccc1C(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
TSHR P16473 1/20 0.39
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
OPRK1 P41145 2/20 0.38
OPRL1 P41146 2/20 0.38
ACHE P22303 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 1/20 0.37
CNR2 P34972 2/20 0.36
NFE2L2 Q16236 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3406218 0.83 IDO1 (0.42) IDO1TDO2CES2CES1OPRM1
SCHEMBL4219819 0.81 IDO1 (0.41) IDO1TDO2CES2CES1OPRM1
SCHEMBL30057869 0.79 ACHE (0.40) IDO1TDO2CES2CES1ACHE
SCHEMBL17289093 0.79 IDO1 (0.39) IDO1TDO2CES2CES1OPRM1
SCHEMBL15352478 0.79 CES2 (0.44) IDO1TDO2CES2CES1ACHE
SCHEMBL213484 0.79 ACHE (0.40) IDO1TDO2CES2CES1ACHE
SCHEMBL15352482 0.79 CES2 (0.48) IDO1TDO2CES2CES1OPRM1
SCHEMBL4763525 0.79 IDO1 (0.39) IDO1TDO2CES2CES1OPRM1
SCHEMBL28443760 0.79 IDO1 (0.44) IDO1TDO2CES2CES1TSHR
SCHEMBL931945 0.79 ACHE (0.40) IDO1TDO2CES2CES1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102617312-B Method for preparing 2-chloro-6-fluorobenzaldehyde DANYANG WANLONG CHEMICAL CO LTD 2014-05-28 CN claimed
CN-109627154-B Preparation method of o-fluorobenzaldehyde 国药集团化学试剂有限公司 2022-02-01 CN disclosed
CN-109111463-A The manufacturing method of aromatic compound DIC株式会社 2019-01-01 CN disclosed
CN-108698982-A FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF 日产化学工业株式会社 2018-10-23 CN disclosed
CN-107428629-A Process for producing alpha-olefin oligomer 三菱化学株式会社 2017-12-01 CN disclosed
CN-104192802-B The by-product hydrochloric acid purifying method of the chloro-6-fluorobenzaldehyde of 2-or analogue ZHEJIANG DAYANG BIOTECH GROUP CO., LTD. (CN) 2016-01-13 CN disclosed
CN-102781884-B Process for producing alpha-olefin oligomer MITSUBISHI CHEMICAL CORP. (JP) 2015-11-25 CN disclosed
CN-104926589-A Process for producing alpha-olefin oligomer MITSUBISHI CHEM CORP 2015-09-23 CN disclosed
CN-104192802-A Purification method of coproduct hydrochloric acid of 2-chloro-6-fluorobenzaldehyde or analogs ZHEJIANG DAYANG BIOTECH GROUP CO LTD 2014-12-10 CN disclosed
CN-102046575-B Therapeutic agent for alzheimer's disease TOKYO INSTITUTE OF TECHNOLOGY (JP) 2014-10-29 CN disclosed
CN-102617312-B Method for preparing 2-chloro-6-fluorobenzaldehyde DANYANG WANLONG CHEMICAL CO LTD 2014-05-28 CN disclosed
CN-103523846-A Treatment method of high-concentration fluoride-containing aromatic hydrocarbon wastewater SHAANXI SHENGMAI PETROLEUM CO 2014-01-22 CN disclosed
CN-103044181-A Method for preparing octene-1 by ethylene tetramerization reaction PETROCHINA CO LTD 2013-04-17 CN disclosed
CN-102918026-A Fungicidal iminoderivatives BASF SE 2013-02-06 CN disclosed
CN-1651142-A Catalyst component used for ethylene oligomerization, preparing process and application thereof DAQING PETROCHEMICAL BRANCH CO (CN) 2005-08-10 CN disclosed
CN-1108193-C Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2003-05-14 CN disclosed
CN-1256968-A Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2000-06-21 CN disclosed
US-4310680-A METAL OR METAL COMPOUND CATALYST DYNAMIT NOBEL AG (DE) 1982-01-12 US disclosed