Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483395 | 0.99 | TRPV1 (0.46) | TRPV1BACE1CTSDKMT2AOPRM1 | |
| SCHEMBL11481607 | 0.89 | BACE1 (0.40) | TRPV1BACE1CTSDOPRM1OPRD1 | |
| SCHEMBL11481567 | 0.88 | TRPV1 (0.40) | TRPV1BACE1CTSDKMT2AOPRM1 | |
| SCHEMBL11474807 | 0.86 | IDO1 (0.41) | TRPV1BACE1CTSDKMT2AIDO1 | |
| SCHEMBL11489365 | 0.85 | KDM1A (0.42) | TRPV1BACE1CTSDKMT2AOPRM1 | |
| SCHEMBL11486581 | 0.85 | ALDH1A1 (0.41) | TRPV1BACE1CTSDKMT2AIDO1 | |
| SCHEMBL11245449 | 0.85 | TRPV1 (0.45) | TRPV1BACE1CTSDKMT2AOPRM1 | |
| SCHEMBL11249928 | 0.84 | TRPV1 (0.44) | TRPV1BACE1CTSDKMT2AOPRM1 | |
| SCHEMBL11261454 | 0.83 | TRPV1 (0.44) | TRPV1BACE1CTSDKMT2AOPRD1 | |
| SCHEMBL11243369 | 0.83 | OPRD1 (0.45) | TRPV1BACE1CTSDKMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |