Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070951 | 0.89 | PRSS1 (0.46) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11560139 | 0.89 | PRSS1 (0.46) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11258943 | 0.88 | PRSS1 (0.47) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL29384484 | 0.88 | PRSS1 (0.47) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11249024 | 0.88 | PRSS1 (0.47) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11260978 | 0.86 | PRSS1 (0.46) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11255138 | 0.85 | PRSS1 (0.45) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11241832 | 0.85 | PRSS1 (0.45) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11247397 | 0.82 | PRSS1 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Cetaben SCHEMBL2112078 | 0.81 | HCAR3 (0.59) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310545-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | claimed |