Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261677 | 0.88 | TSHR (0.43) | CYP19A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11255691 | 0.86 | CYP19A1 (0.42) | CYP19A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11242414 | 0.82 | CYP19A1 (0.59) | CYP19A1CYP3A4TSHRMAPK1CYP3A5 | |
| SCHEMBL11249211 | 0.81 | CYP19A1 (0.40) | CYP19A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11245253 | 0.78 | CYP3A4 (0.46) | CYP19A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11248026 | 0.73 | CYP19A1 (0.47) | CYP19A1CYP3A4TSHRMAPK1CYP3A5 | |
| SCHEMBL11256928 | 0.73 | TSHR (0.43) | CYP19A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11254850 | 0.72 | CHRM2 (0.43) | CYP19A1AHR | |
| SCHEMBL11258472 | 0.70 | MEN1 (0.46) | CYP19A1TSHRMAPK1 | |
| SCHEMBL11255698 | 0.69 | USP2 (0.59) | CYP19A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322442-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |