Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645629 | 0.98 | MAPT (0.41) | MAPTELANESMN1; SMN2EPHX2ALOX15 | |
| SCHEMBL2106281 | 0.92 | CTRC (0.38) | MAPTELANESMN1; SMN2ALOX15 | |
| SCHEMBL11233427 | 0.78 | ELANE (0.38) | MAPTELANE | |
| SCHEMBL23394743 | 0.76 | ACE2 (0.37) | ELANE | |
| SCHEMBL21539633 | 0.76 | LMNA (0.35) | ELANE | |
| SCHEMBL21320791 | 0.76 | ELANE (0.34) | ELANE | |
| SCHEMBL24105931 | 0.75 | PRSS1 (0.37) | MAPTELANE | |
| SCHEMBL20114311 | 0.74 | ELANE (0.33) | ELANE | |
| SCHEMBL30982893 | 0.72 | TYR (0.64) | ELANE | |
| SCHEMBL10878735 | 0.70 | EPHX2 (0.57) | MAPTELANEEPHX2ALOX15ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |