Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860685 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A | |
| SCHEMBL23932523 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30040769 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4901648 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A | |
| SCHEMBL11267330 | 0.71 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A | |
| SCHEMBL14172844 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7291906 | 0.69 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29678249 | 0.67 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A | |
| SCHEMBL307790 | 0.67 | MEN1 (0.62) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A | |
| SCHEMBL4604147 | 0.67 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1BLMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337357-A | 1,4-BENZOTHIAZINE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4268301-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-19 | — | — | US | disclosed |