SCHEMBL4604147

SCHEMBL4604147

O=C(CCl)Nc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.57
KDM1A O60341 1/20 0.57
KMT2A Q03164 8/20 0.56
MEN1 O00255 7/20 0.56
BLM P54132 2/20 0.56
GAA P10253 5/20 0.53
NPC1 O15118 4/20 0.53
LMNA P02545 3/20 0.53
HTT P42858 3/20 0.53
TP53 P04637 2/20 0.53
RAB9A P51151 5/20 0.51
MAPT P10636 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
PKM P14618 2/20 0.51
HPGD P15428 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4011016 0.87 ALDH1A1 (0.65) ALDH1A1KMT2AMEN1BLMNPC1
SCHEMBL13416408 0.85 KDM1A (0.68) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL5429131 0.85 RAB9A (0.56) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL8028208 0.82 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1BLMGAA
SCHEMBL10955276 0.82 KDM1A (0.59) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL968912 0.80 CA1 (0.64) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL9848848 0.80 KDM1A (0.57) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL763528 0.80 KDM1A (0.57) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL4361189 0.80 KDM1A (0.62) ALDH1A1KDM1AKMT2AMEN1GAA
SCHEMBL860003 0.80 KDM1A (0.57) ALDH1A1KDM1AKMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572498-B Stone-like cement artistic decoration material and method for decorating by using same 上海无间建筑设计有限公司 2023-10-20 CN claimed
CN-115572498-A Stone-like cement artistic decorative material and method for decorating by using same 上海无间建筑设计有限公司 2023-01-06 CN claimed
CN-115572498-B Stone-like cement artistic decoration material and method for decorating by using same 上海无间建筑设计有限公司 2023-10-20 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115572498-A Stone-like cement artistic decorative material and method for decorating by using same 上海无间建筑设计有限公司 2023-01-06 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed
WO-2016153242-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CENTRAL NERVOUS SYSTEM DISEASE 재단법인 경기과학기술진흥원 2016-09-29 WO disclosed
CN-101503392-B Aromatic aminomethane compounds, as well as preparation and medical use thereof UNIV CHINA PHARMA 2010-12-29 CN disclosed
CN-100569735-C The synthesis technique of o-chloroacetaminophenol DAQING NEW CENTURY FINE CHEMIC (CN) 2009-12-16 CN disclosed
CN-101503392-A Aromatic aminomethane compounds, as well as preparation and medical use thereof UNIV CHINA PHARMA (CN) 2009-08-12 CN disclosed
EP-0626966-A1 3-SUBSTITUTED IMIDAZO(1,5-A)QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY PHARMACIA & UPJOHN COMPANY (US) 1994-12-07 EP disclosed
EP-0590022-A1 IMIDAZO 1,5-a]QUINOXALINES PHARMACIA & UPJOHN COMPANY (US) 1994-04-06 EP disclosed
WO-1993017025-A1 3-SUBSTITUTED IMIDAZO(1,5-A)QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY THE UPJOHN COMPANY (US) 1993-09-02 WO disclosed
WO-1992022552-A1 IMIDAZO[1,5-a]QUINOXALINES THE UPJOHN COMPANY (US) 1992-12-23 WO disclosed
US-4585774-A Aniline derivatives and cardiotonic composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-04-29 US disclosed
EP-0064878-B1 NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-07-24 EP disclosed
EP-0064878-A1 Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1982-11-17 EP disclosed
US-4245099-A ANTIINFLAMMATORY, ANALGESIC, DIURETIC, ANTIPYRETIC AND HYPOTENSIVE AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1981-01-13 US disclosed
US-4002743-A INSECTICIDES, ACARICIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 ALDH1A1 1196/4885KDM1A 1043/4885KMT2A 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.